Saturday, April 21, 2012

Eurax Hydrocortisone Cream (Novartis Consumer Health)





1. Name Of The Medicinal Product



Eurax® Hydrocortisone Cream


2. Qualitative And Quantitative Composition








Active ingredients:




Crotamiton 10.0% w/w




 



 




Hydrocortisone BP 0.25% w/w



For excipients see section 6.1



3. Pharmaceutical Form



Cream



4. Clinical Particulars



4.1 Therapeutic Indications



Eczema and dermatitis of all types including atopic eczema, photodermatitis, otitis externa, primary irritant and allergic dermatitis, intertrigo, prurigo nodularis, seborrhoeic dermatitis and insect bite reactions.



Route of Administration: Cutaneous use.



4.2 Posology And Method Of Administration



Adults



A thin layer of Eurax Hydrocortisone Cream should be applied to the affected area 2-3 times a day. Occlusive dressings should not be used. Treatment should be limited to 10-14 days or up to 7 days if applied to the face.



Use in the Elderly



Clinical evidence would indicate that no special dosage regime is necessary.



Use in Children



Eurax Hydrocortisone should be used with caution in infants and for not more than 7 days. Eurax Hydrocortisone should not be applied more than once a day to large areas of the body surface in young children.



4.3 Contraindications



Hypersensitivity to any component of the formulation. Bacterial, viral or fungal infections of the skin. Acute exudative dermatoses. Application to ulcerated areas.



4.4 Special Warnings And Precautions For Use



Eurax Hydrocortisone should be used with caution in infants and for not more than 7 days; long-term continuous topical therapy should be avoided since this can lead to adrenal suppression even without occlusion.



Eurax Hydrocortisone should not be allowed to come into contact with the conjunctiva and mucous membranes.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



None known.



4.6 Pregnancy And Lactation



There is inadequate evidence of safety in human pregnancy. Topical administration of corticosteroids to pregnant animals can cause abnormalities of foetal development, including cleft palate and intra-uterine growth retardation. There may therefore be a very small risk of such effects in the human foetus.



It is not known whether the active substances of Eurax Hydrocortisone and/or their metabolites pass into the breast milk after topical administration. Use in lactating mothers should only be at the doctor's discretion.



4.7 Effects On Ability To Drive And Use Machines



None known.



4.8 Undesirable Effects



Occasionally at the site of application signs of irritation such as a burning sensation, itching, contact dermatitis/contact allergy may occur. Treatment should be discontinued if patients experience severe irritation or sensitisation.



4.9 Overdose



Eurax Hydrocortisone is for application to the skin only. If accidental ingestion of large quantities occurs, there is no specific antidote and general measures to eliminate the drug and reduce its absorption should be undertaken. Symptomatic treatment should be administered as appropriate.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



Eurax Hydrocortisone combines the antipruritic action of crotamiton with the anti-inflammatory and anti-allergic properties of hydrocortisone.



5.2 Pharmacokinetic Properties



No pharmacokinetic data on Eurax Hydrocortisone Cream are available.



5.3 Preclinical Safety Data



Not applicable.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Stearyl alcohol



White soft paraffin



Polyoxy 40 stearate



Propyl hydroxybenzoate



Propylene glycol



Methyl hydroxybenzoate



Perfume Givaudan no 45



Sulphuric acid



Purified water



6.2 Incompatibilities



None known



6.3 Shelf Life



30 months



6.4 Special Precautions For Storage



Do not store above 25C



6.5 Nature And Contents Of Container



Collapsible aluminium tube



Pack Size: 30g



6.6 Special Precautions For Disposal And Other Handling



Medicines should be kept out of the reach and sight of children.



7. Marketing Authorisation Holder



Novartis Consumer Health UK Ltd



Trading as



Novartis Consumer Health



Wimblehurst Road



Horsham



West Sussex



RH12 5AB



8. Marketing Authorisation Number(S)



PL 00030/0094



9. Date Of First Authorisation/Renewal Of The Authorisation



Original grant date: 17 January 1991



Date of renewal: 17 January 1996



10. Date Of Revision Of The Text



22 December 2009



Legal category: POM




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