Benazepril

In some countries, this medicine may only be approved for veterinary use.

In the US, Benazepril (benazepril systemic) is a member of the drug class angiotensin converting enzyme inhibitors and is used to treat Diabetic Kidney Disease, Heart Failure, High Blood Pressure and Left Ventricular Dysfunction.

US matches:

• Benazepril


• Benazepril/Hydrochlorothiazide


• Benazepril and hydrochlorothiazide


• Benazepril Hydrochloride


• Benazepril Hydrochloride/Hydrochlorothiazide

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C09AA07

CAS registry number (Chemical Abstracts Service)

0086541-75-5

Chemical Formula

C24-H28-N2-O5

Molecular Weight

424

Therapeutic Category

ACE inhibitor

Chemical Name

1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]-amino]-2,3,4,5-tetrahydro-2-oxo-, [S-(R*,R*)]-

Foreign Names

• Benazeprilum (Latin)
• Benazepril (German)
• Bénazépril (French)
• Benazepril (Spanish)

Generic Names

• Benazepril (OS: DCIT, JAN, BAN)
• Bénazépril (OS: DCF)
• Benazepril Hydrochloride (OS: BANM, USAN)
• CGS 14824 A (IS: Ciba)
• Benazepril Hydrochloride (PH: Ph. Eur. 6, USP 32, BP 2010)

Brand Names

• Benazepril Sandoz
  Hexal, Romania



• Benazepril
  Teva, Israel



• Lotensin HCT (Benazepril and Hydrochlorothiazide)
  Meda, Hungary



• Amlodipine Besylate and Benazepril Hydrochloride (Benazepril and Amlodipine besilate)
  Lupin, United States; Teva USA, United States



• Apo-Benazepril
  Apotex, Canada



• Benace
  Novartis, India



• Benakor
  Gräub, Switzerland



• Benakor (veterinary use)
  Virbac, France



• Benazecare (veterinary use)
  Animalcare Ltd., Luxembourg



• Benazep
  Sawai Seiyaku, Japan



• Benazeplus AL (Benazepril and Hydrochlorothiazide)
  Aliud, Germany



• Benazeplus Stada (Benazepril and Hydrochlorothiazide)
  Stada, Germany



• Benazepril AL
  Aliud, Germany



• Benazepril beta comp (Benazepril and Hydrochlorothiazide)
  Betapharm, Germany



• Benazepril comp. Heumann (Benazepril and Hydrochlorothiazide)
  Heumann, Germany



• Bénazépril EG
  EG Labo, France



• Benazepril HCl
  Teva USA, United States



• Benazepril Heumann
  Heumann, Germany



• Benazepril Hexal
  Hexal, Germany



• Benazepril Hexal comp (Benazepril and Hydrochlorothiazide)
  Hexal, Germany



• Benazepril Hydrochloride and Hydrochlorothiazide (Benazepril and Hydrochlorothiazide)
  Andrx, United States; Genpharm, United States; Mylan, United States; Ranbaxy, United States; Sandoz, United States



• Benazepril Hydrochloride
  Andrx, United States; Apotex, United States; Aurobindo, United States; Biokey, United States; Genpharm, United States; KV Pharmaceutical, United States; Mylan, United States; Ranbaxy, United States; Sandoz, United States; Zydus, United States



• Bénazépril Hydrochlorothiazide EG (Benazepril and Hydrochlorothiazide)
  EG Labo, France



• Bénazépril Mylan
  Mylan, France



• Benazepril STADA
  Stada, Poland



• Benazepril Winthrop comp (Benazepril and Hydrochlorothiazide)
  Winthrop, Germany



• Benazepril with Hydrochlorothiazide (Benazepril and Hydrochlorothiazide)
  Andrx, United States; Eon, United States; Ranbaxy, United States; Sandoz, United States



• Benazepril-1A Pharma
  1A Pharma, Germany



• Benazepril-1A Pharma comp (Benazepril and Hydrochlorothiazide)
  1A Pharma, Germany



• Benazepril-Hexal
  Hexal, Luxembourg



• Boncordin
  Sandoz, Argentina



• Briazide (Benazepril and Hydrochlorothiazide)
  Pierre Fabre Médicament, France



• Briem
  Pierre Fabre Médicament, France



• Chlorowodorek benazeprilu LeVet (veterinary use)
  Produlab Pharma, Poland



• Cibace
  Novartis, South Africa



• Cibacen Cor
  Meda, Germany



• Cibacen
  Meda, Germany; Meda, Denmark; Meda, Ireland; Meda, Iceland; Meda, Italy; Meda, Luxembourg; Meda, Netherlands; Meda Pharm, Greece; Meda Pharma Sau, Spain; Novartis, Belgium; Novartis, Bulgaria; Novartis, Bahrain; Novartis, Switzerland; Novartis, Georgia; Novartis, Ghana; Novartis, Guyana; Novartis, Indonesia; Novartis, Israel; Novartis, Japan; Novartis, Kenya; Novartis, Malta; Novartis, Nigeria; Novartis, Philippines; Novartis, Romania; Novartis, Sudan; Novartis, Turkey; Novartis, Taiwan; Novartis, Tanzania; Novartis, Zimbabwe



• Cibacène
  Meda, France; Meda, France



• Cibadrex
  Novartis, Ghana; Novartis, Kenya; Novartis, Nigeria; Novartis, Sudan; Novartis, Tanzania; Novartis, Zimbabwe



• Cibadrex (Benazepril and Hydrochlorothiazide)
  Meda, Germany; Meda, France; Meda, Luxembourg; Meda Pharm, Greece; Meda Pharma Sau, Spain; Novartis, Bulgaria; Novartis, Bulgaria; Novartis, Bahrain; Novartis, Switzerland; Novartis, South Africa



• Fortekor (veterinary use)
  Novartis, Ireland; Novartis Animal Health, Austria; Novartis Animal Health, Belgium; Novartis Animal Health, United Kingdom; Novartis Animal Health, Italy; Novartis Animal Health, Luxembourg; Novartis Animal Health, Netherlands; Novartis Animal Health, Norway; Novartis Animal Health, New Zealand; Novartis Animal Health, Sweden; Novartis Animal Health, South Africa; Novartis Animal Health Australasia, Australia; Novartis Farma -Produtos Farmaceuticos S.A., Portugal; Novartis Santé Animale, France; Novartis Tiergesundheit, Switzerland; Novartis Tiergesundheit, Germany; Novartis vet., Finland



• Labodrex (Benazepril and Hydrochlorothiazide)
  Meda Pharma Sau, Spain



• Labopal
  Glaxo SmithKline, Spain



• Lisonid
  Actavis Group, Poland



• Lotensin HCT (Benazepril and Hydrochlorothiazide)
  Novartis, United States



• Lotensin
  Meda, Hungary; Novartis, Brazil; Novartis, Canada; Novartis, China; Novartis, Poland; Novartis, Russian Federation; Novartis, United States



• Lotrel (Benazepril and Amlodipine besilate)
  Novartis, United States



• Nelio (veterinary use)
  Sogeval, France



• Prebase
  Towa Yakuhin, Japan



• Tatsujipin
  Tatsumi Kagaku, Japan



• Tensanil
  Savio, Italy



• Zaprace-D (Benazepril and Hydrochlorothiazide)
  Ranbaxy, China



• Zinadril
  Errekappa, Italy

International Drug Name Search

Glossary

BAN	British Approved Name
BANM	British Approved Name (Modified)
DCF	Dénomination Commune Française
DCIT	Denominazione Comune Italiana
IS	Inofficial Synonym
JAN	Japanese Accepted Name
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Rasoltan

Rasoltan may be available in the countries listed below.

Ingredient matches for Rasoltan

Losartan

Losartan is reported as an ingredient of Rasoltan in the following countries:

• Georgia

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Rasoltan in the following countries:

• Bulgaria


• Hungary


• Poland

International Drug Name Search

Celebrex

Celebrex is a brand name of celecoxib, approved by the FDA in the following formulation(s):

CELEBREX (celecoxib - capsule; oral)

• 
  Manufacturer: GD SEARLE
  
  Approval date: December 31, 1998
  
  Strength(s): 100MG, 200MG
  


• 
  Manufacturer: GD SEARLE
  
  Approval date: August 29, 2002
  
  Strength(s): 400MG ^[RLD]


• 
  Manufacturer: GD SEARLE
  
  Approval date: December 15, 2006
  
  Strength(s): 50MG
  

Has a generic version of Celebrex been approved?

No. There is currently no therapeutically equivalent version of Celebrex available.

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Celebrex. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.

Related Patents

Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.

• 
  Substituted pyrazolyl benzenesulfonamides
  Patent 5,466,823
  Issued: November 14, 1995
  Inventor(s): Talley; John J. & Penning; Thomas D. & Collins; Paul W. & Rogier, Jr.; Donald J. & Malecha; James W. & Miyashiro; Julie M. & Bertenshaw; Stephen R. & Khanna; Ish K. & Graneto; Matthew J. & Rogers; Roland S. & Carter; Jeffery S.
  Assignee(s): G.D. Searle & Co.
  A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I: ##STR1## or a pharmaceutically-acceptable salt thereof.
  
  Patent expiration dates:
  
  
  • November 30, 2013
    
    ✓ 
    Drug substance
  
  
  
  • May 30, 2014
    
    ✓ 
    Pediatric exclusivity
  
  



• 
  Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
  Patent 5,563,165
  Issued: October 8, 1996
  Inventor(s): Talley; John J. & Penning; Thomas D. & Collins; Paul W. & Rogier, Jr.; Donald J. & Malecha; James W. & Miyashiro; Julie M. & Bertenshaw; Stephen R. & Khanna; Ish K. & Graneto; Matthew J. & Rogers; Roland S. & Carter; Jeffery S.
  Assignee(s): G. D. Searl & Co.
  A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I: ##STR1##
  
  Patent expiration dates:
  
  
  • November 30, 2013
    
    ✓ 
    Drug product
  
  
  
  • May 30, 2014
    
    ✓ 
    Pediatric exclusivity
  
  



• 
  Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
  Patent 5,760,068
  Issued: June 2, 1998
  Inventor(s): Talley; John J. & Penning; Thomas D. & Collins; Paul W. & Rogier, Jr.; Donald J. & Malecha; James W. & Miyashiro; Julie M. & Bertenshaw; Stephen R. & Khanna; Ish K. & Graneto; Matthew J. & Rogers; Roland S. & Carter; Jeffery S. & Docter; Stephen H. & Yu; Stella S.
  Assignee(s): G.D. Searle & Co.
  A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II: ##STR1## or a pharmaceutically-acceptable salt thereof.
  
  Patent expiration dates:
  
  
  • June 2, 2015
    
    ✓ 
    Patent use: TREATMENT OF INFLAMMATION OR AN INFLAMMATION-ASSOCIATED DISORDER
  
  
  
  • December 2, 2015
    
    ✓ 
    Pediatric exclusivity
  
  

See also...

• Celebrex Consumer Information (Drugs.com)
• Celebrex Consumer Information (Wolters Kluwer)
• Celebrex Consumer Information (Cerner Multum)
• Celebrex Advanced Consumer Information (Micromedex)
• Celebrex AHFS DI Monographs (ASHP)
• Celecoxib Consumer Information (Drugs.com)
• Celecoxib Consumer Information (Wolters Kluwer)
• Celecoxib Consumer Information (Cerner Multum)
• Celecoxib Advanced Consumer Information (Micromedex)
• Celecoxib AHFS DI Monographs (ASHP)

Acido Folico L.CH.

Acido Folico L.CH. may be available in the countries listed below.

Ingredient matches for Acido Folico L.CH.

Folic Acid

Folic Acid is reported as an ingredient of Acido Folico L.CH. in the following countries:

• Chile

International Drug Name Search

Atestad

Atestad may be available in the countries listed below.

Ingredient matches for Atestad

Atenolol

Atenolol is reported as an ingredient of Atestad in the following countries:

• Philippines

International Drug Name Search

Almiral

Almiral may be available in the countries listed below.

Ingredient matches for Almiral

Diclofenac

Diclofenac diethylamine (a derivative of Diclofenac) is reported as an ingredient of Almiral in the following countries:

• Slovakia

Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Almiral in the following countries:

• Bahrain


• Bangladesh


• Bulgaria


• Czech Republic


• Estonia


• Ethiopia


• Hong Kong


• Iraq


• Jordan


• Latvia


• Malta


• Oman


• Romania


• Singapore


• Slovakia


• Sri Lanka


• Sudan


• Taiwan


• Yemen

International Drug Name Search

Pupilla

Pupilla may be available in the countries listed below.

Ingredient matches for Pupilla

Benzalkonium Chloride

Benzalkonium chloride (a derivative of Benzalkonium) is reported as an ingredient of Pupilla in the following countries:

• Italy

Naphazoline

Naphazoline nitrate (a derivative of Naphazoline) is reported as an ingredient of Pupilla in the following countries:

• Italy

International Drug Name Search

Emage

Emage may be available in the countries listed below.

Ingredient matches for Emage

Omeprazole

Omeprazole is reported as an ingredient of Emage in the following countries:

• Bangladesh

International Drug Name Search

Cesplon

Cesplon may be available in the countries listed below.

Ingredient matches for Cesplon

Captopril

Captopril is reported as an ingredient of Cesplon in the following countries:

• Spain

International Drug Name Search

Budesonide Spray

Pronunciation: bue-DES-oh-nide
Generic Name: Budesonide
Brand Name: Rhinocort Aqua

Budesonide Spray is used for:

Treating nasal allergy symptoms, including runny nose, nasal congestion, and sneezing. It may also be used for other conditions as determined by your doctor.

Budesonide Spray is a corticosteroid. It works by shrinking swollen and inflamed nasal tissue, and by blocking the action of certain cells and chemicals of the immune system.

Do NOT use Budesonide Spray if:

• you are allergic to any ingredient in Budesonide Spray


• you are taking mifepristone

Contact your doctor or health care provider right away if any of these apply to you.

Before using Budesonide Spray:

Some medical conditions may interact with Budesonide Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a bacterial, viral, fungal, or parasitic infection; chickenpox; tuberculosis (TB); a positive TB skin test; measles; diarrhea; nasal ulcer, surgery, or trauma; or herpes infection in the eye; or if you have had a recent vaccine

Some MEDICINES MAY INTERACT with Budesonide Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Clarithromycin, imidazoles (eg, ketoconazole), hormonal contraceptives (eg, birth control pills), or mifepristone because side effects, such as adrenal suppression effects, may occur


• Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or rifampin because they may decrease Budesonide Spray's effectiveness


• Live vaccines, mifepristone, or ritodrine because the risk of their side effects may be increased by Budesonide Spray


• Hydantoins (eg, phenytoin) because their effectiveness may be decreased by Budesonide Spray

This may not be a complete list of all interactions that may occur. Ask your health care provider if Budesonide Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Budesonide Spray:

Use Budesonide Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Budesonide Spray is for use in the nose.


• Shake well before each use.


• Before using Budesonide Spray for the first time, gently shake the container and prime the pump 8 times.


• Clear your nose before using Budesonide Spray. You may sniff gently to distribute the medicine into your nose, but do not breathe deeply.


• If Budesonide Spray is used daily, the pump does not need to be reprimed. If it is not used for 2 consecutive days, reprime it with 1 spray or until a fine mist appears.


• If Budesonide Spray is not used for more than 14 days, rinse the applicator and reprime it with 2 sprays or until a fine mist appears.


• Use Budesonide Spray on a regular schedule to get the most benefit from it.


• Continue to use Budesonide Spray even if you feel well. Do not miss any doses.


• Throw the bottle away after 120 sprays following the priming of the bottle. You may not get the correct amount of medication in each spray after a certain number of uses. Do not transfer any remaining suspension to another bottle.


• If you miss a dose of Budesonide Spray, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Budesonide Spray.

Important safety information:

• Use caution if you switch from an oral steroid (eg, prednisone) to Budesonide Spray. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.


• Avoid spraying in the eyes.


• Always have a spare inhaler available in case the unit malfunctions or is empty.


• Symptoms can start to improve as soon as 10 hours after you start using Budesonide Spray, and should improve within a few days. If symptoms do not improve within 2 weeks, or if the condition worsens, contact your health care provider.


• If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.


• Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take Budesonide Spray.


• Budesonide Spray should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Budesonide Spray while you are pregnant. Budesonide Spray is found in breast milk. If you are or will be breast-feeding while you use Budesonide Spray, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Budesonide Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bad taste; coughing; headache; hoarseness; nasal irritation or dryness; nausea; sore throat; tightness in the lungs.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); continuing nose discomfort; increased pressure in the eye; infection (eg, fever, chills, sore throat); nosebleeds or soreness; pounding in the chest.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include body discomfort; depression; difficulty breathing; dizziness; exhaustion; fainting; joint pain; loss of appetite; muscle aches; nausea.

Proper storage of Budesonide Spray:

Store Budesonide Spray at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in an upright position. Store away from heat, moisture, and light. Do not store in the bathroom. Do not freeze. Keep Budesonide Spray out of the reach of children and away from pets.

General information:

• If you have any questions about Budesonide Spray, please talk with your doctor, pharmacist, or other health care provider.


• Budesonide Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Budesonide Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Budesonide resources

• Budesonide Use in Pregnancy & Breastfeeding
• Budesonide Drug Interactions
• Budesonide Support Group
• 3 Reviews for Budesonide - Add your own review/rating

Compare Budesonide with other medications

• Hay Fever

Allopurinol AL

Allopurinol AL may be available in the countries listed below.

Ingredient matches for Allopurinol AL

Allopurinol

Allopurinol is reported as an ingredient of Allopurinol AL in the following countries:

• Germany

International Drug Name Search

Diurapid

Diurapid may be available in the countries listed below.

Ingredient matches for Diurapid

Furosemide

Furosemide is reported as an ingredient of Diurapid in the following countries:

• Germany

International Drug Name Search